Dichloromethane → 4-(4-Trifluoromethoxybenzoyl)-piperidine

HRID 1141041Notes

Reaction equation

HRID 1141041 reaction equation
[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[N:8]1[CH2:9][CH2:10][CH:11]([C:14]([c:15]2[cH:16][cH:17][c:18]([O:21][C:22]([F:23])([F:24])[F:25])[cH:19][cH:20]2)=[O:26])[CH2:12][CH2:13]1.[CH2:34]([Cl:35])[Cl:36].[Cl:27][C:28]([O:29][CH2:30][CH2:31][Cl:32])=[O:33]>>[NH:8]1[CH2:9][CH2:10][CH:11]([C:14]([c:15]2[cH:16][cH:17][c:18]([O:21][C:22]([F:23])([F:24])[F:25])[cH:19][cH:20]2)=[O:26])[CH2:12][CH2:13]1

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 123052-Chloroethyl chloroformateHCID 230811761-Benzyl-4-(4-trifluoromethoxybenzoyl)piperidine

Product 1

HCID 230814584-(4-Trifluoromethoxybenzoyl)-piperidine

Sources & evidence

ORD record
ord-e4d4db114df543aba73132c244816ca5
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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