2-Cyclohexyloxy-5-methanesulfonyl-benzoic acid → 2-[4-(2-Cyclohexyloxy-5-methanesulfonyl-benzoyl)-piperazin-1-yl]-thiazole-5-carbonitrile

HRID 1141135Notes

Reaction equation

HRID 1141135 reaction equation
[CH:1]1([O:7][c:8]2[c:9]([C:10](=[O:11])[OH:12])[cH:13][c:14]([S:17](=[O:18])(=[O:19])[CH3:20])[cH:15][cH:16]2)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6]1.[N:21]1([c:27]2[s:28][c:29]([C:32]#[N:33])[cH:30][n:31]2)[CH2:22][CH2:23][NH:24][CH2:25][CH2:26]1>>[CH:1]1([O:7][c:8]2[c:9]([C:10](=[O:12])[N:24]3[CH2:23][CH2:22][N:21]([c:27]4[s:28][c:29]([C:32]#[N:33])[cH:30][n:31]4)[CH2:26][CH2:25]3)[cH:13][c:14]([S:17](=[O:18])(=[O:19])[CH3:20])[cH:15][cH:16]2)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6]1

Participants

3

Reactant 2

HCID 211002212-Cyclohexyloxy-5-methanesulfonyl-benzoic acidHCID 211002572-Piperazin-1-yl-thiazole-5-carbonitrile

Product 1

HCID 211002092-[4-(2-Cyclohexyloxy-5-methanesulfonyl-benzoyl)-piperazin-1-yl]-thiazole-5-carbonitrile

Sources & evidence

ORD record
ord-9752d6b1f93043c8a3cafa4713c3def4
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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