Acetic Acid → 3-[(1-Methylpyrrolidin-2-yl)methoxy]-5-(trifluoromethyl)aniline

HRID 114141Notes

Reaction equation

HRID 114141 reaction equation
[C:22]([OH:23])(=[O:24])[CH3:25].[CH3:1][N:2]1[CH:3]([CH2:7][O:8][c:9]2[cH:10][c:11]([N+:19]([O-:20])=[O:21])[cH:12][c:13]([C:15]([F:16])([F:17])[F:18])[cH:14]2)[CH2:4][CH2:5][CH2:6]1.[CH3:26][OH:27]>>[CH3:1][N:2]1[CH:3]([CH2:7][O:8][c:9]2[cH:10][c:11]([NH2:19])[cH:12][c:13]([C:15]([F:16])([F:17])[F:18])[cH:14]2)[CH2:4][CH2:5][CH2:6]1

Participants

4

Reactant 3

HCID 176Acetic AcidHCID 887MethanolHCID 219594761-Methyl-2-(3-nitro-5-trifluoromethyl-phenoxymethyl)-pyrrolidine

Product 1

HCID 219595523-[(1-Methylpyrrolidin-2-yl)methoxy]-5-(trifluoromethyl)aniline

Sources & evidence

ORD record
ord-085802734b9f4a69a026bf7ebc6c3d72
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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