5,6,7,8-Tetrahydro-3-(trifluoromethyl)-1,6-naphthyridine → [4-(2,5-dimethylpyrrol-1-yl)-1-propan-2-ylcyclopent-2-en-1-yl]-[3-(trifluoromethyl)-7,8-dihydro-5H-1,6-naphthyridin-6-yl]methanone

HRID 114146Notes

Reaction equation

HRID 114146 reaction equation
[CH3:1][c:2]1[n:3]([CH:8]2[CH:9]=[CH:10][C:11]([C:13](=[O:14])[OH:15])([CH:16]([CH3:17])[CH3:18])[CH2:12]2)[c:4]([CH3:7])[cH:5][cH:6]1.[F:19][C:20]([c:21]1[cH:22][n:23][c:24]2[c:29]([cH:30]1)[CH2:28][NH:27][CH2:26][CH2:25]2)([F:31])[F:32]>>[CH3:1][c:2]1[n:3]([CH:8]2[CH:9]=[CH:10][C:11]([C:13](=[O:15])[N:27]3[CH2:26][CH2:25][c:24]4[n:23][cH:22][c:21]([C:20]([F:19])([F:31])[F:32])[cH:30][c:29]4[CH2:28]3)([CH:16]([CH3:17])[CH3:18])[CH2:12]2)[c:4]([CH3:7])[cH:5][cH:6]1

Participants

3

Reactant 2

HCID 114810975,6,7,8-Tetrahydro-3-(trifluoromethyl)-1,6-naphthyridineHCID 72833403(1S,4S)-4-(2,5-diMethyl-1H-pyrrol-1-yl)-1-(propan-2-yl)cyclopent-2-ene-1-carboxylic acid

Product 1

HCID 72361980[4-(2,5-dimethylpyrrol-1-yl)-1-propan-2-ylcyclopent-2-en-1-yl]-[3-(trifluoromethyl)-7,8-dihydro-5H-1,6-naphthyridin-6-yl]methanone

Sources & evidence

ORD record
ord-642c3c3f245e476e823a38db80698207
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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