Potassium Cation → 6-{4-[Methyl(2-trifluoromethylphenyl)amino]piperidin-1-YL}pyridazine-3-carboxylic acid (2-cyclopropylethyl)amide

HRID 1141502Notes

Reaction equation

HRID 1141502 reaction equation
[CH3:1][N:2]([c:3]1[c:4]([C:9]([F:10])([F:11])[F:12])[cH:5][cH:6][cH:7][cH:8]1)[CH:13]1[CH2:14][CH2:15][NH:16][CH2:17][CH2:18]1.[CH:19]1([CH2:22][CH2:23][NH:24][C:25](=[O:26])[c:27]2[n:28][n:29][c:30]([Cl:33])[cH:31][cH:32]2)[CH2:20][CH2:21]1.[K+:34].[K+:35].[O-:36][C:37]([O-:38])=[O:39].[O:40]1[CH2:41][CH2:42][O:43][CH2:44][CH2:45]1>>[CH3:1][N:2]([c:3]1[c:4]([C:9]([F:10])([F:11])[F:12])[cH:5][cH:6][cH:7][cH:8]1)[CH:13]1[CH2:14][CH2:15][N:16]([c:30]2[n:29][n:28][c:27]([C:25]([NH:24][CH2:23][CH2:22][CH:19]3[CH2:20][CH2:21]3)=[O:26])[cH:32][cH:31]2)[CH2:17][CH2:18]1

Participants

6

Reactant 5

HCID 813Potassium Cation2×HCID 19660Carbonate IonHCID 312751,4-DioxaneHCID 578744214-Piperidinamine, N-methyl-N-[2-(trifluoromethyl)phenyl]-HCID 655615656-Chloro-N-(2-cyclopropylethyl)pyridazine-3-carboxamide

Product 1

HCID 117120206-{4-[Methyl(2-trifluoromethylphenyl)amino]piperidin-1-YL}pyridazine-3-carboxylic acid (2-cyclopropylethyl)amide

Sources & evidence

ORD record
ord-b79cc30f85624a24babba8662d32c2e9
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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