Potassium Cation → 5-(3-Bromophenyl)-5-(difluoromethyl)-3-morpholinone

HRID 114159Notes

Reaction equation

HRID 114159 reaction equation
[Br:1][c:2]1[cH:3][c:4]([C:8]([CH:9]([F:10])[F:11])([CH2:12][OH:13])[NH:14][C:15]([CH2:16][Cl:17])=[O:18])[cH:5][cH:6][cH:7]1.[CH3:19][C:20]([CH3:21])([O-:22])[CH3:23].[CH3:26][C:27]([OH:28])([CH3:29])[CH3:30].[K+:24].[OH2:25]>>[Br:1][c:2]1[cH:3][c:4]([C:8]2([CH:9]([F:10])[F:11])[CH2:12][O:13][CH2:16][C:15](=[O:18])[NH:14]2)[cH:5][cH:6][cH:7]1

Participants

6

Reactant 5

HCID 813Potassium CationHCID 962WaterHCID 6386tert-ButanolHCID 45749132-Methylpropan-2-olateHCID 66665688N-[1-(3-Bromo-phenyl)-2,2-difluoro-1-hydroxymethyl-ethyl]-2-chloro-acetamide

Product 1

HCID 666654075-(3-Bromophenyl)-5-(difluoromethyl)-3-morpholinone

Sources & evidence

ORD record
ord-e61a4cdc26f54c449a24f13ac9c85788
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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