Dichloromethane → 5-bromo-1-methyl-3-(pyrimidin-4-ylamino)pyridin-2(1H)-one
Reaction equation
[Br:8][c:9]1[c:10](=[O:17])[n:11]([CH3:16])[cH:12][c:13]([Br:15])[cH:14]1.[C:18](=[O:19])([O-:20])[O-:21].[Cl:30][CH2:31][Cl:32].[Cs+:22].[Cs+:23].[NH2:1][c:2]1[cH:3][cH:4][n:5][cH:6][n:7]1.[O:24]1[CH2:25][CH2:26][O:27][CH2:28][CH2:29]1.[O:35]=[C:36]([CH:37]=[CH:38][c:39]1[cH:40][cH:41][cH:42][cH:43][cH:44]1)[CH:45]=[CH:46][c:47]1[cH:48][cH:49][cH:50][cH:51][cH:52]1.[O:53]=[C:54]([CH:55]=[CH:56][c:57]1[cH:58][cH:59][cH:60][cH:61][cH:62]1)[CH:63]=[CH:64][c:65]1[cH:66][cH:67][cH:68][cH:69][cH:70]1.[O:71]=[C:72]([CH:73]=[CH:74][c:75]1[cH:76][cH:77][cH:78][cH:79][cH:80]1)[CH:81]=[CH:82][c:83]1[cH:84][cH:85][cH:86][cH:87][cH:88]1.[Pd:33].[Pd:34]>>[NH:1]([c:2]1[cH:3][cH:4][n:5][cH:6][n:7]1)[c:9]1[c:10](=[O:17])[n:11]([CH3:16])[cH:12][c:13]([Br:15])[cH:14]1Participants
9
Reactant 8
Product 1
Sources & evidence
- ORD record
- ord-be03015731604f98a6c2e1a0bdc6134b
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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