Ammonia → 6-(4-Fluorophenyl)-2-methylpyrido[3,2-d]pyrimidin-4-amine

HRID 1142156Notes

Reaction equation

HRID 1142156 reaction equation
[CH3:1][c:2]1[n:3][c:4]([Cl:19])[c:5]2[c:6]([n:7]1)[cH:8][cH:9][c:10](-[c:12]1[cH:13][cH:14][c:15]([F:18])[cH:16][cH:17]1)[n:11]2.[CH3:39][OH:40].[NH2:21][c:22]1[c:23]2[n:24][c:25](-[c:26]3[cH:27][cH:28][c:29]([F:30])[cH:31][cH:32]3)[cH:33][cH:34][c:35]2[n:36][cH:37][n:38]1.[NH3:20]>>[CH3:1][c:2]1[n:3][c:4]([NH2:21])[c:5]2[c:6]([n:7]1)[cH:8][cH:9][c:10](-[c:12]1[cH:13][cH:14][c:15]([F:18])[cH:16][cH:17]1)[n:11]2

Participants

5

Reactant 4

HCID 222AmmoniaHCID 887MethanolHCID 576983546-(4-Fluorophenyl)pyrido[3,2-d]pyrimidin-4-amineHCID 576983684-Chloro-6-(4-fluorophenyl)-2-methylpyrido[3,2-d]pyrimidine

Product 1

HCID 576983296-(4-Fluorophenyl)-2-methylpyrido[3,2-d]pyrimidin-4-amine

Sources & evidence

ORD record
ord-7ee5233c1b8949deb90ea99f45764854
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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