2-[(4-Fluorophenoxy)methyl]oxirane → 1'-[3-(4-fluorophenoxy)-2-hydroxypropyl]-9-methoxyspiro[3H-benzo[h][1,4]benzoxathiine-2,4'-piperidine]-5,6-dione

HRID 1142190Notes

Reaction equation

HRID 1142190 reaction equation
[CH3:1][O:2][c:3]1[cH:4][cH:5][c:6]2[c:20]([cH:21]1)[C:10]1=[C:9]([C:8](=[O:22])[C:7]2=[O:23])[S:14][CH2:13][C:12]2([O:11]1)[CH2:15][CH2:16][NH:17][CH2:18][CH2:19]2.[F:24][c:25]1[cH:26][cH:27][c:28]([O:29][CH2:30][CH:31]2[O:32][CH2:33]2)[cH:34][cH:35]1>>[CH3:1][O:2][c:3]1[cH:4][cH:5][c:6]2[c:20]([cH:21]1)[C:10]1=[C:9]([C:8](=[O:22])[C:7]2=[O:23])[S:14][CH2:13][C:12]2([O:11]1)[CH2:15][CH2:16][N:17]([CH2:33][CH:31]([CH2:30][O:29][c:28]1[cH:27][cH:26][c:25]([F:24])[cH:35][cH:34]1)[OH:32])[CH2:18][CH2:19]2

Participants

3

Reactant 2

HCID 27247922-[(4-Fluorophenoxy)methyl]oxiraneHCID 576618849-Methoxyspiro[naphtho[1,2-b][1,4]oxathiine-2,4'-piperidine]-5,6-dione

Product 1

HCID 765862501'-[3-(4-fluorophenoxy)-2-hydroxypropyl]-9-methoxyspiro[3H-benzo[h][1,4]benzoxathiine-2,4'-piperidine]-5,6-dione

Sources & evidence

ORD record
ord-ac925649dbc242ed8b25044b810b8491
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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