Toluene → [1-(6-Fluoropyridin-3-yl)-pyrrolidin-3-yl]-carbamic acid tert-butyl ester
Reaction equation
[Br:14][c:15]1[cH:16][cH:17][c:18]([F:21])[n:19][cH:20]1.[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([NH:7][CH:8]1[CH2:9][NH:10][CH2:11][CH2:12]1)=[O:13].[C:22](=[O:23])([O-:24])[O-:25].[CH3:28][c:29]1[cH:30][cH:31][cH:32][cH:33][cH:34]1.[Cs+:26].[Cs+:27]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([NH:7][CH:8]1[CH2:9][N:10]([c:15]2[cH:16][cH:17][c:18]([F:21])[n:19][cH:20]2)[CH2:11][CH2:12]1)=[O:13]Participants
6
Sources & evidence
- ORD record
- ord-c3ea7a3efb8b4f5cb80f51bd8b27ffaf
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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