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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1142270Generated: October 25, 2026

4-(4-methylpiperazin-1-yl)-6-[3-methyl-7-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3,4-dihydroisoquinolin-2(1H)-yl]pyrimidin-2-amine → 2-(3-{2-[2-Amino-6-(4-methylpiperazin-1-yl)pyrimidin-4-yl]-3-methyl-1,2,3,4-tetrahydroisoquinolin-7-yl}-1H-pyrazol-1-yl)ethanol

https://huagongshe.com/reaction/1142270

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(4-methylpiperazin-1-yl)-6-[3-methyl-7-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3,4-dihydroisoquinolin-2(1H)-yl]pyrimidin-2-amineHCID 59402256—
Reactant2-(3-bromo-1H-pyrazol-1-yl)ethan-1-olHCID 59402299—
Product2-(3-{2-[2-Amino-6-(4-methylpiperazin-1-yl)pyrimidin-4-yl]-3-methyl-1,2,3,4-tetrahydroisoquinolin-7-yl}-1H-pyrazol-1-yl)ethanolHCID 46700984—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (7/10)
ORD IDord-488f14f8748e4aed8e18dfe36c045cb1
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (7/10)