4-(Difluoromethoxy)benzyl Bromide → 4-chloro-N-[[4-(difluoromethoxy)phenyl]methyl]-N-(5,5-difluoro-2-oxoazepan-3-yl)benzenesulfonamide
Reaction equation
[Cl:1][c:2]1[cH:3][cH:4][c:5]([S:8](=[O:9])(=[O:10])[NH:11][CH:12]2[C:13](=[O:21])[NH:14][CH2:15][CH2:16][C:17]([F:19])([F:20])[CH2:18]2)[cH:6][cH:7]1.[F:22][CH:23]([O:24][c:25]1[cH:26][cH:27][c:28]([CH2:29][Br:30])[cH:31][cH:32]1)[F:33]>>[Cl:1][c:2]1[cH:3][cH:4][c:5]([S:8](=[O:9])(=[O:10])[N:11]([CH:12]2[C:13](=[O:21])[NH:14][CH2:15][CH2:16][C:17]([F:19])([F:20])[CH2:18]2)[CH2:29][c:28]2[cH:27][cH:26][c:25]([O:24][CH:23]([F:22])[F:33])[cH:32][cH:31]2)[cH:6][cH:7]1Participants
3
Sources & evidence
- ORD record
- ord-f2d802f99b0246a39389bb0e45f70ecb
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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