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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1142486Generated: November 2, 2026

Tetrahydrofuran → 4-((5-bromo-2-trityl-2H-1,2,4-triazol-3-yl)(5-ethoxy-2-fluoro-3-isopropoxyphenyl)methylamino)benzonitrile

https://huagongshe.com/reaction/1142486

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrahydrofuranHCID 8028—
Reactant(E)-4-(5-ethoxy-2-fluoro-3-isopropoxybenzylideneamino)benzonitrileHCID 57804014—
Reactant3,5-dibromo-1-trityl-1H-1,2,4-triazoleHCID 57804036—
ReactantButyllithiumHCID 178418339—
Product4-((5-bromo-2-trityl-2H-1,2,4-triazol-3-yl)(5-ethoxy-2-fluoro-3-isopropoxyphenyl)methylamino)benzonitrileHCID 68814516—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (7/10)
ORD IDord-0154d99e65bb491dbf02c5316cfc5586
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (7/10)