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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1142541Generated: November 1, 2026

Dichloromethane → 5-Chloro-N-{2-[3-(isocyanatomethyl)benzyl]-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl}-2-thiophenecarboxamide

https://huagongshe.com/reaction/1142541

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDichloromethaneHCID 6344—
ReactantDiphosgeneHCID 10426—
ReactantProton spongeHCID 88675—
ReactantN-{2-[3-(Aminomethyl)benzyl]-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl}-5-chloro-2-thiophenecarboxamideHCID 22337012—
Product5-Chloro-N-{2-[3-(isocyanatomethyl)benzyl]-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl}-2-thiophenecarboxamideHCID 22337098—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (7/10)
ORD IDord-4501f3be656441baac5c7e76d466859a
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (7/10)