4-(Trifluoromethyl)benzaldehyde → 2,2-Dimethyl-5-({6-fluoro-7-[(methylsulfanyl)methyl]-1H-indol-3-yl}[4-(trifluoromethyl)phenyl]methyl)-1,3-dioxane-4,6-dione

HRID 1142664Notes

Reaction equation

HRID 1142664 reaction equation
[Cl:26][c:27]1[cH:28][cH:29][c:30]([CH:33]([CH:34]2[C:35](=[O:43])[O:36][C:37]([CH3:41])([CH3:42])[O:38][C:39]2=[O:40])[c:44]2[cH:45][nH:46][c:47]3[c:48]([CH2:54][S:55][CH3:56])[c:49]([F:53])[cH:50][cH:51][c:52]23)[cH:31][cH:32]1.[F:14][C:15]([c:16]1[cH:17][cH:18][c:19]([CH:20]=[O:21])[cH:22][cH:23]1)([F:24])[F:25].[F:1][c:2]1[c:3]([CH2:4][S:5][CH3:6])[c:7]2[c:8]([cH:9][cH:10][nH:11]2)[cH:12][cH:13]1>>[F:14][C:15]([F:24])([F:25])[c:27]1[cH:28][cH:29][c:30]([CH:33]([CH:34]2[C:35](=[O:43])[O:36][C:37]([CH3:41])([CH3:42])[O:38][C:39]2=[O:40])[c:44]2[cH:45][nH:46][c:47]3[c:48]([CH2:54][S:55][CH3:56])[c:49]([F:53])[cH:50][cH:51][c:52]23)[cH:31][cH:32]1

Participants

4

Reactant 3

HCID 679964-(Trifluoromethyl)benzaldehydeHCID 583922596-Fluoro-7-[(methylsulfanyl)methyl]-1H-indoleHCID 583925085-[(4-Chlorophenyl){6-fluoro-7-[(methylsulfanyl)methyl]-1H-indol-3-yl}methyl]-2,2-dimethyl-1,3-dioxane-4,6-dione

Product 1

HCID 583921882,2-Dimethyl-5-({6-fluoro-7-[(methylsulfanyl)methyl]-1H-indol-3-yl}[4-(trifluoromethyl)phenyl]methyl)-1,3-dioxane-4,6-dione

Sources & evidence

ORD record
ord-239705a785544eb8bdd3eeb7370a5821
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

Loading…