2-Bromomethyl-5-(4-trifluoromethyl-phenyl)-pyrimidine → 3-{2-Methyl-4-[5-(4-trifluoromethyl-phenyl)-pyrimidin-2-ylmethoxy]-phenyl}-propionic acid ethyl ester
Reaction equation
[Br:16][CH2:17][c:18]1[n:19][cH:20][c:21](-[c:24]2[cH:25][cH:26][c:27]([C:30]([F:31])([F:32])[F:33])[cH:28][cH:29]2)[cH:22][n:23]1.[CH2:1]([CH3:2])[O:3][C:4]([CH2:5][CH2:6][c:7]1[c:8]([CH3:14])[cH:9][c:10]([OH:13])[cH:11][cH:12]1)=[O:15]>>[CH2:1]([CH3:2])[O:3][C:4]([CH2:5][CH2:6][c:7]1[c:8]([CH3:14])[cH:9][c:10]([O:13][CH2:17][c:18]2[n:19][cH:20][c:21](-[c:24]3[cH:25][cH:26][c:27]([C:30]([F:31])([F:32])[F:33])[cH:28][cH:29]3)[cH:22][n:23]2)[cH:11][cH:12]1)=[O:15]Participants
3
Sources & evidence
- ORD record
- ord-e918a03934894ee4beff8de4120bd240
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
Loading…