4-Iodobenzonitrile → 5-(4-Cyanophenyl)-1H-indole-2-carboxylic acid ethyl ester

HRID 1142972Notes

Reaction equation

HRID 1142972 reaction equation
[CH2:1]([CH3:2])[O:3][C:4](=[O:5])[c:6]1[nH:7][c:8]2[cH:9][cH:10][c:11]([B:15]3[O:16][C:17]([CH3:18])([CH3:19])[C:20]([CH3:21])([CH3:22])[O:23]3)[cH:12][c:13]2[cH:14]1.[I:24][c:25]1[cH:26][cH:27][c:28]([C:29]#[N:30])[cH:31][cH:32]1>>[CH2:1]([CH3:2])[O:3][C:4](=[O:5])[c:6]1[nH:7][c:8]2[cH:9][cH:10][c:11](-[c:25]3[cH:26][cH:27][c:28]([C:29]#[N:30])[cH:31][cH:32]3)[cH:12][c:13]2[cH:14]1

Participants

3

Reactant 2

HCID 764674-IodobenzonitrileHCID 21111505Ethyl 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole-2-carboxylate

Product 1

HCID 687004805-(4-Cyanophenyl)-1H-indole-2-carboxylic acid ethyl ester

Sources & evidence

ORD record
ord-17b2fa7fc811490398e2999787176518
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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