Methanol → Tert-butyl 5-[[3,5-bis(trifluoromethyl)phenyl]methylamino]-7-methyl-8-(trifluoromethyl)-2,3,4,5-tetrahydro-1-benzazepine-1-carboxylate
Reaction equation
[BH4-:41].[CH3:43][OH:44].[F:1][C:2]([c:3]1[cH:4][c:5]([CH:6]=[O:7])[cH:8][c:9]([C:11]([F:12])([F:13])[F:14])[cH:10]1)([F:15])[F:16].[NH2:17][CH:18]1[c:19]2[c:20]([cH:32][c:33]([C:37]([F:38])([F:39])[F:40])[c:34]([CH3:36])[cH:35]2)[N:21]([C:25](=[O:26])[O:27][C:28]([CH3:29])([CH3:30])[CH3:31])[CH2:22][CH2:23][CH2:24]1.[Na+:42]>>[F:1][C:2]([c:3]1[cH:4][c:5]([CH2:6][NH:17][CH:18]2[c:19]3[c:20]([cH:32][c:33]([C:37]([F:38])([F:39])[F:40])[c:34]([CH3:36])[cH:35]3)[N:21]([C:25](=[O:26])[O:27][C:28]([CH3:29])([CH3:30])[CH3:31])[CH2:22][CH2:23][CH2:24]2)[cH:8][c:9]([C:11]([F:12])([F:13])[F:14])[cH:10]1)([F:15])[F:16]Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-d30ccc2c03224d139fc9d29ecf4e19c4
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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