5-Amino-3-(4-tert-butyl-phenyl)-4-cyano-thiophene-2-carboxylic acid methyl ester → 5-Amino-4-cyano-3-(4-iodo-phenyl)-thiophene-2-carboxylic acid ethyl ester
Reaction equation
[CH2:23]([CH3:24])[O:25][C:26](=[O:27])[c:28]1[s:29][c:30]([N:42]=[N+:43]=[N-:44])[c:31]([C:40]#[N:41])[c:32]1-[c:33]1[cH:34][cH:35][c:36]([I:39])[cH:37][cH:38]1.[CH3:1][O:2][C:3]([c:4]1[s:5][c:6]([NH2:7])[c:8]([C:9]#[N:10])[c:11]1-[c:12]1[cH:13][cH:14][c:15]([C:16]([CH3:17])([CH3:18])[CH3:19])[cH:20][cH:21]1)=[O:22]>>[CH2:23]([CH3:24])[O:25][C:26](=[O:27])[c:28]1[s:29][c:30]([NH2:42])[c:31]([C:40]#[N:41])[c:32]1-[c:33]1[cH:34][cH:35][c:36]([I:39])[cH:37][cH:38]1Participants
3
Sources & evidence
- ORD record
- ord-7301de3e7f7f4de0b3dd5f651a37436b
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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