5-bromo-2-(4-fluorophenyl)-4-methoxy-3(2H)-pyridazinone → 2-(4-Fluorophenyl)-4-methoxy-5-[4-(methylthio)phenyl]-3(2H)-pyridazinone

HRID 1143283Notes

Reaction equation

HRID 1143283 reaction equation
[CH3:18][S:19][c:20]1[cH:21][cH:22][c:23]([B:26]([OH:27])[OH:28])[cH:24][cH:25]1.[F:1][c:2]1[cH:3][cH:4][c:5](-[n:8]2[n:9][cH:10][c:11]([Br:17])[c:12]([O:15][CH3:16])[c:13]2=[O:14])[cH:6][cH:7]1>>[F:1][c:2]1[cH:3][cH:4][c:5](-[n:8]2[n:9][cH:10][c:11](-[c:23]3[cH:22][cH:21][c:20]([S:19][CH3:18])[cH:25][cH:24]3)[c:12]([O:15][CH3:16])[c:13]2=[O:14])[cH:6][cH:7]1

Participants

3

Reactant 2

HCID 14874955-bromo-2-(4-fluorophenyl)-4-methoxy-3(2H)-pyridazinoneHCID 27339594-(Methylthio)phenylboronic acid

Product 1

HCID 219341922-(4-Fluorophenyl)-4-methoxy-5-[4-(methylthio)phenyl]-3(2H)-pyridazinone

Sources & evidence

ORD record
ord-e4a7414828f3496db76371242a77fa31
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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