Pyridine → N-(4-(1,3-benzodioxol-5-yl)-3-{2-[(5-chloro-2-pyrimidinyl)oxy]ethoxy}-1-methyl-1H-pyrazol-5-yl)-1-methyl-1H-imidazole-4-sulfonamide

HRID 1143352Notes

Reaction equation

HRID 1143352 reaction equation
[CH3:1][n:2]1[cH:3][n:4][c:5]([S:7](=[O:8])(=[O:9])[Cl:10])[cH:6]1.[CH3:38][N:39]([c:40]1[cH:41][cH:42][cH:43][cH:44][n:45]1)[CH3:46].[O:11]1[CH2:12][O:13][c:14]2[c:15]1[cH:16][cH:17][c:18](-[c:20]1[c:21]([O:27][CH2:28][CH2:29][O:30][c:31]3[n:32][cH:33][c:34]([Cl:37])[cH:35][n:36]3)[n:22][n:23]([CH3:26])[c:24]1[NH2:25])[cH:19]2.[cH:47]1[cH:48][cH:49][n:50][cH:51][cH:52]1>>[CH3:1][n:2]1[cH:3][n:4][c:5]([S:7](=[O:8])(=[O:9])[NH:25][c:24]2[c:20](-[c:18]3[cH:17][cH:16][c:15]4[c:14]([cH:19]3)[O:13][CH2:12][O:11]4)[c:21]([O:27][CH2:28][CH2:29][O:30][c:31]3[n:32][cH:33][c:34]([Cl:37])[cH:35][n:36]3)[n:22][n:23]2[CH3:26])[cH:6]1

Participants

5

Reactant 4

HCID 1049PyridineHCID 218852-DimethylaminopyridineHCID 27368871-methyl-1H-imidazole-4-sulfonyl chlorideHCID 22281927HCID 22281927, compound

Product 1

HCID 9871777N-(4-(1,3-benzodioxol-5-yl)-3-{2-[(5-chloro-2-pyrimidinyl)oxy]ethoxy}-1-methyl-1H-pyrazol-5-yl)-1-methyl-1H-imidazole-4-sulfonamide

Sources & evidence

ORD record
ord-315d03d5f19b47388cbffad03aa9e668
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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