[5-(4-Chloro-phenyl)-4-cyclopentylmethyl-2-(2-ethoxy-4-methoxy-phenyl)-4,5-dihydro-imidazol-1-yl]-(4-methyl-piperazin-1-yl)-methanone → [5-(4-Chloro-phenyl)-4-cyclohexyl-2-(2-ethoxy-4-methoxy-phenyl)-4,5-dihydro-imidazol-1-yl]-(4-methyl-piperazin-1-yl)-methanone

HRID 1143366Notes

Reaction equation

HRID 1143366 reaction equation
[Cl:1][c:2]1[cH:3][cH:4][c:5]([CH:6]2[NH:7][C:8]([c:9]3[cH:10][cH:11][c:12]([O:13][CH3:14])[cH:15][c:16]3[O:17][CH2:18][CH3:19])=[N:20][CH:21]2[CH:22]2[CH2:23][CH2:24][CH2:25][CH2:26][CH2:27]2)[cH:28][cH:29]1.[Cl:30][c:31]1[cH:32][cH:33][c:34]([CH:37]2[CH:38]([CH2:62][CH:63]3[CH2:64][CH2:65][CH2:66][CH2:67]3)[N:39]=[C:40]([c:51]3[c:52]([O:59][CH2:60][CH3:61])[cH:53][c:54]([O:57][CH3:58])[cH:55][cH:56]3)[N:41]2[C:42](=[O:43])[N:44]2[CH2:45][CH2:46][N:47]([CH3:50])[CH2:48][CH2:49]2)[cH:35][cH:36]1>>[Cl:30][c:31]1[cH:32][cH:33][c:34]([CH:37]2[CH:38]([CH:62]3[CH2:63][CH2:67][CH2:66][CH2:65][CH2:64]3)[N:39]=[C:40]([c:51]3[c:52]([O:59][CH2:60][CH3:61])[cH:53][c:54]([O:57][CH3:58])[cH:55][cH:56]3)[N:41]2[C:42](=[O:43])[N:44]2[CH2:45][CH2:46][N:47]([CH3:50])[CH2:48][CH2:49]2)[cH:35][cH:36]1

Participants

3

Reactant 2

HCID 11193096[5-(4-Chloro-phenyl)-4-cyclopentylmethyl-2-(2-ethoxy-4-methoxy-phenyl)-4,5-dihydro-imidazol-1-yl]-(4-methyl-piperazin-1-yl)-methanoneHCID 178467015HCID 178467015, compound

Product 1

HCID 11226480[5-(4-Chloro-phenyl)-4-cyclohexyl-2-(2-ethoxy-4-methoxy-phenyl)-4,5-dihydro-imidazol-1-yl]-(4-methyl-piperazin-1-yl)-methanone

Sources & evidence

ORD record
ord-54ad3638adcd48a6a69f09e5c3a0f864
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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