Dichloromethane → 1-(3,4-Difluorophenyl)-N-(4-fluorophenyl)-3,4-dihydroisoquinoline-2(1H)-carboxamide
Reaction equation
[Cl:29][CH2:30][Cl:31].[F:19][c:20]1[cH:21][cH:22][c:23]([N:26]=[C:27]=[O:28])[cH:24][cH:25]1.[F:1][c:2]1[cH:3][c:4]([CH:9]2[NH:10][CH2:11][CH2:12][c:13]3[cH:14][cH:15][cH:16][cH:17][c:18]32)[cH:5][cH:6][c:7]1[F:8]>>[F:1][c:2]1[cH:3][c:4]([CH:9]2[N:10]([C:27]([NH:26][c:23]3[cH:22][cH:21][c:20]([F:19])[cH:25][cH:24]3)=[O:28])[CH2:11][CH2:12][c:13]3[cH:14][cH:15][cH:16][cH:17][c:18]32)[cH:5][cH:6][c:7]1[F:8]Participants
4
Sources & evidence
- ORD record
- ord-bb8fdda023cf475fb32e1e0a6f39037a
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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