Ethyl chloroformate → 4-({1-[4-(2-Cyclopropylmethoxy-4-methoxy-phenyl)-5H-pyrrolo[3,2-d]pyrimidin-7-yl]-methanoyl}-amino)-piperidine-1-carboxylic acid ethyl ester

HRID 1143377Notes

Reaction equation

HRID 1143377 reaction equation
[Cl:32][C:33](=[O:34])[O:35][CH2:36][CH3:37].[NH:1]1[CH2:2][CH2:3][CH:4]([NH:7][C:8](=[O:9])[c:10]2[cH:11][nH:12][c:13]3[c:14]2[n:15][cH:16][n:17][c:18]3-[c:19]2[c:20]([O:27][CH2:28][CH:29]3[CH2:30][CH2:31]3)[cH:21][c:22]([O:25][CH3:26])[cH:23][cH:24]2)[CH2:5][CH2:6]1>>[N:1]1([C:33](=[O:34])[O:35][CH2:36][CH3:37])[CH2:2][CH2:3][CH:4]([NH:7][C:8](=[O:9])[c:10]2[cH:11][nH:12][c:13]3[c:14]2[n:15][cH:16][n:17][c:18]3-[c:19]2[c:20]([O:27][CH2:28][CH:29]3[CH2:30][CH2:31]3)[cH:21][c:22]([O:25][CH3:26])[cH:23][cH:24]2)[CH2:5][CH2:6]1

Participants

3

Reactant 2

HCID 10928Ethyl chloroformateHCID 668676844-(2-cyclopropylmethoxy-4-methoxy-phenyl)-5H-pyrrolo[3,2-d]pyrimidine-7-carboxylic acid piperidin-4-ylamide

Product 1

HCID 442083504-({1-[4-(2-Cyclopropylmethoxy-4-methoxy-phenyl)-5H-pyrrolo[3,2-d]pyrimidin-7-yl]-methanoyl}-amino)-piperidine-1-carboxylic acid ethyl ester

Sources & evidence

ORD record
ord-807752f60a824d98b41fbef6928ff2a4
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

Loading…