Toluene → N-(5-cyclohexyl-2-(methyloxy)phenyl)-N'-(3-methyl-4-((3-(2-(methylamino)-4-pyrimidinyl)-2-pyridinyl)oxy)phenyl)urea

HRID 1143391Notes

Reaction equation

HRID 1143391 reaction equation
[CH3:41][c:42]1[cH:43][cH:44][cH:45][cH:46][cH:47]1.[CH:1]1([c:7]2[cH:8][c:9]([N:15]=[C:16]=[O:17])[c:10]([O:13][CH3:14])[cH:11][cH:12]2)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6]1.[NH2:18][c:19]1[cH:20][c:21]([CH3:40])[c:22]([O:23][c:24]2[n:25][cH:26][cH:27][cH:28][c:29]2-[c:30]2[n:31][c:32]([NH:36][CH3:37])[n:33][cH:34][cH:35]2)[cH:38][cH:39]1>>[CH:1]1([c:7]2[cH:8][c:9]([NH:15][C:16](=[O:17])[NH:18][c:19]3[cH:20][c:21]([CH3:40])[c:22]([O:23][c:24]4[n:25][cH:26][cH:27][cH:28][c:29]4-[c:30]4[n:31][c:32]([NH:36][CH3:37])[n:33][cH:34][cH:35]4)[cH:38][cH:39]3)[c:10]([O:13][CH3:14])[cH:11][cH:12]2)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6]1

Participants

4

Reactant 3

HCID 1140TolueneHCID 469295424-(2-(4-amino-2-methylphenoxy)pyridin-3-yl)-N-methylpyrimidin-2-amineHCID 83918541HCID 83918541, compound

Product 1

HCID 58588072N-(5-cyclohexyl-2-(methyloxy)phenyl)-N'-(3-methyl-4-((3-(2-(methylamino)-4-pyrimidinyl)-2-pyridinyl)oxy)phenyl)urea

Sources & evidence

ORD record
ord-3f84e6682b67499da1773dab95cde308
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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