Acetic Acid → 1-(2,2-dimethoxyethyl)-7-fluoro-3,4-dihydro-1,5-naphthyridin-2(1H)-one
Reaction equation
[Br:21][CH2:22][CH:23]([O:24][CH3:25])[O:26][CH3:27].[CH3:29][S:30](=[O:31])[CH3:32].[CH3:33][C:34](=[O:35])[OH:36].[CH3:37][c:38]1[cH:39][cH:40][cH:41][cH:42][cH:43]1.[F:9][c:10]1[cH:11][n:12][c:13]2[c:18]([cH:19]1)[NH:17][C:16](=[O:20])[CH2:15][CH2:14]2.[K+:6].[K+:7].[K+:8].[OH2:28].[P:1]([O-:2])([O-:3])([O-:4])=[O:5]>>[F:9][c:10]1[cH:11][n:12][c:13]2[c:18]([cH:19]1)[N:17]([CH2:22][CH:23]([O:24][CH3:25])[O:26][CH3:27])[C:16](=[O:20])[CH2:15][CH2:14]2Participants
9
Reactant 8
Product 1
Sources & evidence
- ORD record
- ord-c4f941999e054b9fa320edc2cfe84ec7
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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