Potassium Cation → Bis(3,5-bis(trifluoromethyl)phenyl)(pyrrolidin-2-yl)methanol

HRID 1143726Notes

Reaction equation

HRID 1143726 reaction equation
[CH3:38][OH:39].[F:1][C:2]([c:3]1[cH:4][c:5]([C:13]2([c:22]3[cH:23][c:24]([C:32]([F:33])([F:34])[F:35])[cH:25][c:26]([C:28]([F:29])([F:30])[F:31])[cH:27]3)[CH:14]3[N:15]([C:16](=[O:18])[O:17]2)[CH2:19][CH2:20][CH2:21]3)[cH:6][c:7]([C:9]([F:10])([F:11])[F:12])[cH:8]1)([F:36])[F:37].[K+:41].[OH-:40]>>[F:1][C:2]([c:3]1[cH:4][c:5]([C:13]([CH:14]2[NH:15][CH2:19][CH2:20][CH2:21]2)([OH:17])[c:22]2[cH:23][c:24]([C:32]([F:33])([F:34])[F:35])[cH:25][c:26]([C:28]([F:29])([F:30])[F:31])[cH:27]2)[cH:6][c:7]([C:9]([F:10])([F:11])[F:12])[cH:8]1)([F:36])[F:37]

Participants

5

Reactant 4

HCID 813Potassium CationHCID 887MethanolHCID 961HydroxideHCID 59420146(R)-1,1-bis(3,5-bis(trifluoromethyl)phenyl)tetrahydropyrrolo[1,2-c]oxazol-3(1H)-one

Product 1

HCID 53421132Bis(3,5-bis(trifluoromethyl)phenyl)(pyrrolidin-2-yl)methanol

Sources & evidence

ORD record
ord-02a91ce9870443a9aa4fbb5bb7830b53
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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