9-Chloro-11-(chlorocarbonyl)-5,11-dihydro-6H-pyrido[2,3-b][1,4]benzodiazepin-6-one → 9-Chloro-5,11-dihydro-11-[[3-[2-(1-pyrrolidinyl)ethyl]-1-piperidinyl]carbonyl]-6H-pyrido[2,3-b][1,4]benzodiazepin-6-one

HRID 1143781Notes

Reaction equation

HRID 1143781 reaction equation
[Cl:1][c:2]1[cH:3][c:4]2[c:5]([cH:19][cH:20]1)[C:6](=[O:18])[NH:7][c:8]1[c:9]([n:14][cH:15][cH:16][cH:17]1)[N:10]2[C:11](=[O:12])[Cl:13].[N:21]1([CH2:26][CH2:27][CH:28]2[CH2:29][NH:30][CH2:31][CH2:32][CH2:33]2)[CH2:22][CH2:23][CH2:24][CH2:25]1>>[Cl:1][c:2]1[cH:3][c:4]2[c:5]([cH:19][cH:20]1)[C:6](=[O:18])[NH:7][c:8]1[c:9]([n:14][cH:15][cH:16][cH:17]1)[N:10]2[C:11](=[O:12])[N:30]1[CH2:29][CH:28]([CH2:27][CH2:26][N:21]2[CH2:22][CH2:23][CH2:24][CH2:25]2)[CH2:33][CH2:32][CH2:31]1

Participants

3

Reactant 2

HCID 142099769-Chloro-11-(chlorocarbonyl)-5,11-dihydro-6H-pyrido[2,3-b][1,4]benzodiazepin-6-oneHCID 150573123-(2-(Pyrrolidin-1-yl)ethyl)piperidine

Product 1

HCID 143696619-Chloro-5,11-dihydro-11-[[3-[2-(1-pyrrolidinyl)ethyl]-1-piperidinyl]carbonyl]-6H-pyrido[2,3-b][1,4]benzodiazepin-6-one

Sources & evidence

ORD record
ord-dd4b6370f83441b1a0256c448bf053bc
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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