Dichloromethane → 2-propyl-2-(1-triisopropylsilanyl-1H-pyrrolo[2,3-b]pyridine-5-carbonyl)-pyrrolidine-1-carboxylic acid tert-butyl ester
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[C:9]([CH2:13][CH2:14][CH3:15])([CH:16]([c:17]2[cH:18][c:19]3[c:20]([n:21][cH:22]2)[n:23]([Si:26]([CH:27]([CH3:28])[CH3:29])([CH:30]([CH3:31])[CH3:32])[CH:33]([CH3:34])[CH3:35])[cH:24][cH:25]3)[OH:36])[CH2:10][CH2:11][CH2:12]1.[CH3:37][C:38]([O:39][I:40]1([O:50][C:51]([CH3:52])=[O:53])([O:54][C:55]([CH3:56])=[O:57])[c:41]2[c:42]([cH:43][cH:44][cH:45][cH:46]2)[C:47](=[O:48])[O:49]1)=[O:58].[Cl:59][CH2:60][Cl:61]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[C:9]([CH2:13][CH2:14][CH3:15])([C:16]([c:17]2[cH:18][c:19]3[c:20]([n:21][cH:22]2)[n:23]([Si:26]([CH:27]([CH3:28])[CH3:29])([CH:30]([CH3:31])[CH3:32])[CH:33]([CH3:34])[CH3:35])[cH:24][cH:25]3)=[O:36])[CH2:10][CH2:11][CH2:12]1Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-e55916efa086443c8e50fab6c2b891ca
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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