Methanol → 2-Chloro-N-(2,4-difluorophenyl)-4-methoxynicotinamide
Reaction equation
[CH3:1][O-:2].[CH3:24][OH:25].[Cl:4][c:5]1[c:6]([C:7](=[O:8])[NH:9][c:10]2[c:11]([F:17])[cH:12][c:13]([F:16])[cH:14][cH:15]2)[c:18]([I:22])[cH:19][cH:20][n:21]1.[Na+:3].[OH2:23]>>[CH3:1][O:2][c:18]1[c:6]([C:7](=[O:8])[NH:9][c:10]2[c:11]([F:17])[cH:12][c:13]([F:16])[cH:14][cH:15]2)[c:5]([Cl:4])[n:21][cH:20][cH:19]1Participants
6
Sources & evidence
- ORD record
- ord-6f9911fbe493478aa0677c85b8512f14
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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