3-Aminophenol → N4-[3-[[4-(ethoxycarbonyl)piperidino]carbonyl]phenyl]-5-fluoro-N2-(3-hydroxyphenyl)-2,4-pyrimidinediamine
Reaction equation
[Cl:1][c:2]1[n:3][cH:4][c:5]([F:28])[c:6]([NH:8][c:9]2[cH:10][c:11]([C:15](=[O:16])[N:17]3[CH2:18][CH2:19][CH:20]([C:23](=[O:24])[O:25][CH2:26][CH3:27])[CH2:21][CH2:22]3)[cH:12][cH:13][cH:14]2)[n:7]1.[OH:29][c:30]1[cH:31][c:32]([NH2:33])[cH:34][cH:35][cH:36]1>>[c:2]1([NH:33][c:32]2[cH:31][c:30]([OH:29])[cH:36][cH:35][cH:34]2)[n:3][cH:4][c:5]([F:28])[c:6]([NH:8][c:9]2[cH:10][c:11]([C:15](=[O:16])[N:17]3[CH2:18][CH2:19][CH:20]([C:23](=[O:24])[O:25][CH2:26][CH3:27])[CH2:21][CH2:22]3)[cH:12][cH:13][cH:14]2)[n:7]1Participants
3
Sources & evidence
- ORD record
- ord-6ddcf2cae9c54c8daa93bc0ebcbe88c5
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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