Potassium Cation → Methyl 3-amino-5-bromothiophene-2-carboxylate

HRID 1144386Notes

Reaction equation

HRID 1144386 reaction equation
[Br:1][c:2]1[cH:3][c:4]([NH:11][C:12](=[O:13])[C:14]([F:15])([F:16])[F:17])[c:5]([C:7](=[O:8])[O:9][CH3:10])[s:6]1.[CH3:18][OH:19].[K+:21].[K+:22].[O-:23][C:24]([O-:25])=[O:26].[OH2:20]>>[Br:1][c:2]1[cH:3][c:4]([NH2:11])[c:5]([C:7](=[O:8])[O:9][CH3:10])[s:6]1

Participants

6

Reactant 5

HCID 813Potassium Cation2×HCID 887MethanolHCID 962WaterHCID 19660Carbonate IonHCID 56965789Methyl 5-bromo-3-(2,2,2-trifluoroacetamido)thiophene-2-carboxylate

Product 1

HCID 20158931Methyl 3-amino-5-bromothiophene-2-carboxylate

Sources & evidence

ORD record
ord-f6c88faf401e4fa8b8158fc0a472e8b3
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

Loading…