7-(chloromethyl)-3-methyl-5H-[1,3]thiazolo[3,2-a]pyrimidin-5-one → 7-[(6-{2-[3-Chloro-4-(cyclopropylmethoxy)phenyl]ethyl}-6-cyclopentyl-4-hydroxy-2-oxo-5,6-dihydro-2H-pyran-3-yl)methyl]-3-methyl-5H-[1,3]thiazolo[3,2-a]pyrimidin-5-one
Reaction equation
[Cl:14][CH2:15][c:16]1[n:17]([CH3:18])[n:19][c:20]([CH3:21])[n:22]1.[Cl:1][CH2:2][c:3]1[n:4][c:5]2[n:6]([c:7](=[O:9])[cH:8]1)[c:10]([CH3:13])[cH:11][s:12]2.[Cl:23][c:24]1[cH:25][c:26]([CH2:35][CH2:36][C:37]2([CH:45]3[CH2:46][CH2:47][CH2:48][CH2:49]3)[CH2:38][C:39](=[O:44])[CH2:40][C:41](=[O:43])[O:42]2)[cH:27][cH:28][c:29]1[O:30][CH2:31][CH:32]1[CH2:33][CH2:34]1>>[CH2:2]([c:3]1[n:4][c:5]2[n:6]([c:7](=[O:9])[cH:8]1)[c:10]([CH3:13])[cH:11][s:12]2)[C:40]1=[C:39]([OH:44])[CH2:38][C:37]([CH2:36][CH2:35][c:26]2[cH:25][c:24]([Cl:23])[c:29]([O:30][CH2:31][CH:32]3[CH2:33][CH2:34]3)[cH:28][cH:27]2)([CH:45]2[CH2:46][CH2:47][CH2:48][CH2:49]2)[O:42][C:41]1=[O:43]Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-295b95da691049c08c1585a9862fca7f
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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