Dichloromethane → tert-butyl ({4-[2-(1-azetidin-3-yl-1H-pyrazol-5-yl)-4-chlorophenoxy]-3-cyanophenyl}sulfonyl)1,3-thiazol-4-ylcarbamate
Reaction equation
[CH3:55][N:56]([CH3:57])[c:58]1[c:59]2[c:60]([cH:61][cH:62][cH:63][c:64]2[N:65]([CH3:66])[CH3:67])[cH:68][cH:69][cH:70]1.[Cl:1][c:2]1[cH:3][c:4](-[c:33]2[cH:34][cH:35][n:36][n:37]2[CH:38]2[CH2:39][N:40]([CH:42]([c:43]3[cH:44][cH:45][cH:46][cH:47][cH:48]3)[c:49]3[cH:50][cH:51][cH:52][cH:53][cH:54]3)[CH2:41]2)[c:5]([O:6][c:7]2[c:8]([C:29]#[N:30])[cH:9][c:10]([S:13](=[O:14])(=[O:15])[N:16]([C:17]([O:18][C:19]([CH3:20])([CH3:21])[CH3:22])=[O:23])[c:24]3[n:25][cH:26][s:27][cH:28]3)[cH:11][cH:12]2)[cH:31][cH:32]1.[Cl:71][C:72]([O:73][CH:74]([Cl:75])[CH3:76])=[O:77].[Cl:78][CH2:79][Cl:80]>>[Cl:1][c:2]1[cH:3][c:4](-[c:33]2[cH:34][cH:35][n:36][n:37]2[CH:38]2[CH2:39][NH:40][CH2:41]2)[c:5]([O:6][c:7]2[c:8]([C:29]#[N:30])[cH:9][c:10]([S:13](=[O:14])(=[O:15])[N:16]([C:17]([O:18][C:19]([CH3:20])([CH3:21])[CH3:22])=[O:23])[c:24]3[n:25][cH:26][s:27][cH:28]3)[cH:11][cH:12]2)[cH:31][cH:32]1Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-e4457741124b4147875d14e4757a9855
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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