Pyridine → 2-[5-fluoro-1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl]pyrimidine-4,5,6-triamine
Reaction equation
[F:1][c:2]1[cH:3][c:4]2[c:5]([n:6][cH:7]1)[n:8]([CH2:22][c:23]1[c:24]([F:29])[cH:25][cH:26][cH:27][cH:28]1)[n:9][c:10]2-[c:11]1[n:12][c:13]([NH2:21])[c:14]([N+:18]([O-:19])=[O:20])[c:15]([NH2:17])[n:16]1.[Pd:36].[cH:30]1[cH:31][cH:32][n:33][cH:34][cH:35]1>>[F:1][c:2]1[cH:3][c:4]2[c:5]([n:6][cH:7]1)[n:8]([CH2:22][c:23]1[c:24]([F:29])[cH:25][cH:26][cH:27][cH:28]1)[n:9][c:10]2-[c:11]1[n:12][c:13]([NH2:21])[c:14]([NH2:18])[c:15]([NH2:17])[n:16]1Participants
4
Sources & evidence
- ORD record
- ord-8453ce1472754d08a944f225f1ebc319
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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