Acetate → 7-Bromo-3-chloro-1-fluoro-5',6'-dihydrospiro[chromeno[2,3-c]pyridine-5,4'-[1,3]oxazin]-2'-amine
Reaction equation
[CH3:23][C:24](=[O:25])[O-:26].[CH3:30][CH2:31][OH:32].[N:27]#[C:28][Br:29].[NH2:1][C:2]1([CH2:19][CH2:20][OH:21])[c:3]2[cH:4][c:5]([Br:18])[cH:6][cH:7][c:8]2[O:9][c:10]2[c:11]([F:17])[n:12][c:13]([Cl:16])[cH:14][c:15]21.[Na+:22]>>[N:1]1=[C:28]([NH2:27])[O:21][CH2:20][CH2:19][C:2]12[c:3]1[cH:4][c:5]([Br:18])[cH:6][cH:7][c:8]1[O:9][c:10]1[c:11]([F:17])[n:12][c:13]([Cl:16])[cH:14][c:15]12Participants
6
Sources & evidence
- ORD record
- ord-9f66afae9e8744e1851553599b73dbd4
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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