Ethanol → Tert-butyl 3-[1-(2-aminoethoxy)-1-(3-chlorophenyl)ethyl]piperidine-1-carboxylate

HRID 1144639Notes

Reaction equation

HRID 1144639 reaction equation
[CH3:40][CH2:41][OH:42].[Cl:1][c:2]1[cH:3][c:4]([C:8]([CH3:9])([O:10][CH2:11][CH2:12][N:13]2[C:14](=[O:15])[c:16]3[c:17]([cH:18][cH:19][cH:20][cH:21]3)[C:22]2=[O:23])[CH:24]2[CH2:25][N:26]([C:30](=[O:31])[O:32][C:33]([CH3:34])([CH3:35])[CH3:36])[CH2:27][CH2:28][CH2:29]2)[cH:5][cH:6][cH:7]1.[NH2:38][NH2:39].[OH2:37]>>[Cl:1][c:2]1[cH:3][c:4]([C:8]([CH3:9])([O:10][CH2:11][CH2:12][NH2:13])[CH:24]2[CH2:25][N:26]([C:30](=[O:31])[O:32][C:33]([CH3:34])([CH3:35])[CH3:36])[CH2:27][CH2:28][CH2:29]2)[cH:5][cH:6][cH:7]1

Participants

5

Reactant 4

HCID 702EthanolHCID 962WaterHCID 9321HydrazineHCID 72529720Tert-butyl 3-[1-(3-chlorophenyl)-1-[2-(1,3-dioxoisoindol-2-yl)ethoxy]ethyl]piperidine-1-carboxylate

Product 1

HCID 72529637Tert-butyl 3-[1-(2-aminoethoxy)-1-(3-chlorophenyl)ethyl]piperidine-1-carboxylate

Sources & evidence

ORD record
ord-a2539623ef6e43b8be0d86f9f6f367ab
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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