2-(4-Benzyl-2-oxo-1,3-oxazolidine-3-carbonyl)-3-methylbutane-1-sulfonyl chloride → 4-Benzyl-3-[2-[[4-[5-(4-chlorophenyl)pyrimidin-2-yl]piperidin-1-yl]sulfonylmethyl]-3-methylbutanoyl]-1,3-oxazolidin-2-one

HRID 1144754Notes

Reaction equation

HRID 1144754 reaction equation
[CH2:20]([c:21]1[cH:22][cH:23][cH:24][cH:25][cH:26]1)[CH:27]1[N:28]([C:33]([CH:34]([CH:35]([CH3:36])[CH3:37])[CH2:38][S:39](=[O:40])(=[O:41])[Cl:42])=[O:43])[C:29](=[O:32])[O:30][CH2:31]1.[Cl:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[cH:9][n:10][c:11]([CH:14]3[CH2:15][CH2:16][NH:17][CH2:18][CH2:19]3)[n:12][cH:13]2)[cH:6][cH:7]1>>[Cl:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[cH:9][n:10][c:11]([CH:14]3[CH2:15][CH2:16][N:17]([S:39]([CH2:38][CH:34]([C:33]([N:28]4[CH:27]([CH2:20][c:21]5[cH:22][cH:23][cH:24][cH:25][cH:26]5)[CH2:31][O:30][C:29]4=[O:32])=[O:43])[CH:35]([CH3:36])[CH3:37])(=[O:40])=[O:41])[CH2:18][CH2:19]3)[n:12][cH:13]2)[cH:6][cH:7]1

Participants

3

Reactant 2

HCID 226466772-(4-Benzyl-2-oxo-1,3-oxazolidine-3-carbonyl)-3-methylbutane-1-sulfonyl chlorideHCID 226466975-(4-Chlorophenyl)-2-piperidin-4-ylpyrimidine

Product 1

HCID 226467264-Benzyl-3-[2-[[4-[5-(4-chlorophenyl)pyrimidin-2-yl]piperidin-1-yl]sulfonylmethyl]-3-methylbutanoyl]-1,3-oxazolidin-2-one

Sources & evidence

ORD record
ord-b9afc9d4716e45f7843fe4eedadfa2d2
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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