Benzene → 1-Bromo-3-(4'-fluoro-4-biphenylyl)-butan-3-ol

HRID 1144947Notes

Reaction equation

HRID 1144947 reaction equation
[F:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[cH:9][cH:10][c:11]([C:14]([CH2:15][CH2:16][OH:17])([CH3:18])[OH:19])[cH:12][cH:13]2)[cH:6][cH:7]1.[P:26]([Br:27])([Br:28])[Br:29].[cH:20]1[cH:21][cH:22][n:23][cH:24][cH:25]1.[cH:30]1[cH:31][cH:32][cH:33][cH:34][cH:35]1>>[F:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[cH:9][cH:10][c:11]([C:14]([CH2:15][CH2:16][Br:27])([CH3:18])[OH:19])[cH:12][cH:13]2)[cH:6][cH:7]1

Participants

5

Reactant 4

HCID 241BenzeneHCID 1049PyridineHCID 24614Phosphorus tribromideHCID 213965083-(4'-Fluoro-4-biphenylyl)-1,3-butanediol

Product 1

HCID 213965141-Bromo-3-(4'-fluoro-4-biphenylyl)-butan-3-ol

Sources & evidence

ORD record
ord-e815f070fa5c4d49b5f3f1376f8a64e4
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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