Benzene → 8-{3-[Chloro-(4-chloro-phenyl)-methyl]-phenyl}-6-isopropyl-quinoline

HRID 1145131Notes

Reaction equation

HRID 1145131 reaction equation
[Cl:1][c:2]1[cH:3][cH:4][c:5]([CH:8]([OH:9])[c:10]2[cH:11][c:12](-[c:16]3[cH:17][c:18]([CH:26]([CH3:27])[CH3:28])[cH:19][c:20]4[cH:21][cH:22][cH:23][n:24][c:25]34)[cH:13][cH:14][cH:15]2)[cH:6][cH:7]1.[S:29]([Cl:30])([Cl:31])=[O:32].[cH:33]1[cH:34][cH:35][cH:36][cH:37][cH:38]1>>[Cl:1][c:2]1[cH:3][cH:4][c:5]([CH:8]([c:10]2[cH:11][c:12](-[c:16]3[cH:17][c:18]([CH:26]([CH3:27])[CH3:28])[cH:19][c:20]4[cH:21][cH:22][cH:23][n:24][c:25]34)[cH:13][cH:14][cH:15]2)[Cl:31])[cH:6][cH:7]1

Participants

4

Reactant 3

HCID 241BenzeneHCID 24386Thionyl ChlorideHCID 22350111(4-Chloro-phenyl)-[3-(6-isopropyl-quinolin-8-yl)-phenyl]-methanol

Product 1

HCID 223501108-{3-[Chloro-(4-chloro-phenyl)-methyl]-phenyl}-6-isopropyl-quinoline

Sources & evidence

ORD record
ord-36a3668e6111497cb22050d7b6b56b35
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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