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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1145142Generated: October 29, 2026

2-Chloro-4-isocyanato-1-(trifluoromethyl)benzene → 1-N-[3-chloro-4-(trifluoromethyl)phenyl]-4-[4-(8-hydroxy-6-azaspiro[2.5]octan-6-yl)-4-oxobutyl]-6-methyl-5-oxopiperazine-1,3-dicarboxamide

https://huagongshe.com/reaction/1145142

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Chloro-4-isocyanato-1-(trifluoromethyl)benzeneHCID 14368497—
ReactantBenzyl 5-carbamoyl-4-[4-(8-hydroxy-6-azaspiro[2.5]octan-6-yl)-4-oxobutyl]-2-methyl-3-oxopiperazine-1-carboxylateHCID 67074381—
Product1-N-[3-chloro-4-(trifluoromethyl)phenyl]-4-[4-(8-hydroxy-6-azaspiro[2.5]octan-6-yl)-4-oxobutyl]-6-methyl-5-oxopiperazine-1,3-dicarboxamideHCID 75951831—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (7/10)
ORD IDord-bc1ecc33ba754e57b8910c0c20f73813
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (7/10)