2-(4-Bromo-thiazol-2-yl)-6-methyl-4-(4-trifluoromethyl-phenyl)-pyridine → 5-{2-[6-Methyl-4-(4-trifluoromethyl-phenyl)-pyridin-2-yl]-thiazol-4-yl}-thiophene-2-sulfonic acid tert-butylamide

HRID 1145143Notes

Reaction equation

HRID 1145143 reaction equation
[Br:1][c:2]1[n:3][c:4](-[c:7]2[n:8][c:9]([CH3:23])[cH:10][c:11](-[c:13]3[cH:14][cH:15][c:16]([C:19]([F:20])([F:21])[F:22])[cH:17][cH:18]3)[cH:12]2)[s:5][cH:6]1.[C:24]([CH3:25])([CH3:26])([CH3:27])[NH:28][S:29](=[O:30])(=[O:31])[c:32]1[s:33][c:34]([B:37]2[O:38][C:39]([CH3:40])([CH3:41])[C:42]([CH3:43])([CH3:44])[O:45]2)[cH:35][cH:36]1>>[c:2]1(-[c:34]2[s:33][c:32]([S:29]([NH:28][C:24]([CH3:25])([CH3:26])[CH3:27])(=[O:30])=[O:31])[cH:36][cH:35]2)[n:3][c:4](-[c:7]2[n:8][c:9]([CH3:23])[cH:10][c:11](-[c:13]3[cH:14][cH:15][c:16]([C:19]([F:20])([F:21])[F:22])[cH:17][cH:18]3)[cH:12]2)[s:5][cH:6]1

Participants

3

Reactant 2

HCID 574687942-(4-Bromo-thiazol-2-yl)-6-methyl-4-(4-trifluoromethyl-phenyl)-pyridineHCID 57468817N-tert-butyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)thiophene-2-sulfonamide

Product 1

HCID 247598725-{2-[6-Methyl-4-(4-trifluoromethyl-phenyl)-pyridin-2-yl]-thiazol-4-yl}-thiophene-2-sulfonic acid tert-butylamide

Sources & evidence

ORD record
ord-65b9e142b25e4a3e89c4cd33fba85933
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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