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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1145263Generated: October 30, 2026

Dichloromethane → 2,2,2-Trichloro-1-{10-[(3-methoxy-2'-methyl-[1,1'-biphenyl]-4-yl)carbonyl]-10,11-dihydro-5H-pyrrolo[2,1-c][1,4]benzodiazepin-3-yl}ethanone

https://huagongshe.com/reaction/1145263

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDichloromethaneHCID 6344—
ReactantTrichloroacetyl chlorideHCID 6420—
ReactantDiisopropylethylamineHCID 81531—
Reactant(10,11-dihydro-5H-pyrrolo[2,1-c][1,4]benzodiazepin-10-yl)-[3-methoxy-2'-methyl-[1,1'-biphenyl]-4-yl]-methanoneHCID 21947713—
Product2,2,2-Trichloro-1-{10-[(3-methoxy-2'-methyl-[1,1'-biphenyl]-4-yl)carbonyl]-10,11-dihydro-5H-pyrrolo[2,1-c][1,4]benzodiazepin-3-yl}ethanoneHCID 21947875—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (7/10)
ORD IDord-fc0d4112a7914bd4b82e89ccd18d9978
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (7/10)