m-Xylyl bromide → ethyl N-tert-butoxycarbonyl-4-(3-nitrobenzyl)piperidine-4-carboxylate

HRID 1145586Notes

Reaction equation

HRID 1145586 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][CH:11]([C:14](=[O:15])[O:16][CH2:17][CH3:18])[CH2:12][CH2:13]1.[CH3:19][c:20]1[cH:21][c:22]([CH2:26][Br:27])[cH:23][cH:24][cH:25]1.[N+:28](=[O:29])([O-:30])[c:31]1[cH:32][c:33]([CH2:34][Br:35])[cH:36][cH:37][cH:38]1>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][C:11]([C:14](=[O:15])[O:16][CH2:17][CH3:18])([CH2:34][c:33]2[cH:32][c:31]([N+:28](=[O:29])[O-:30])[cH:38][cH:37][cH:36]2)[CH2:12][CH2:13]1

Participants

4

Reactant 3

HCID 12099m-Xylyl bromideHCID 77568Benzene, 1-(bromomethyl)-3-nitro-HCID 27588121-Tert-butyl 4-ethyl piperidine-1,4-dicarboxylate

Product 1

HCID 53931544ethyl N-tert-butoxycarbonyl-4-(3-nitrobenzyl)piperidine-4-carboxylate

Sources & evidence

ORD record
ord-e9b3647df923481ca3f715bb1e6fa302
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

Loading…