Methanol → 3-(Piperidin-4-yl)quinolin-2(1H)-one

HRID 1145669Notes

Reaction equation

HRID 1145669 reaction equation
[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[N:8]1[CH2:9][CH2:10][CH:11]([c:14]2[c:15](=[O:24])[nH:16][c:17]3[cH:18][cH:19][cH:20][cH:21][c:22]3[cH:23]2)[CH2:12][CH2:13]1.[CH3:27][OH:28].[H:25][H:26].[OH-:29].[OH-:31].[Pd+2:30]>>[NH:8]1[CH2:9][CH2:10][CH:11]([c:14]2[c:15](=[O:24])[nH:16][c:17]3[cH:18][cH:19][cH:20][cH:21][c:22]3[cH:23]2)[CH2:12][CH2:13]1

Participants

6

Reactant 5

HCID 887MethanolHCID 961Hydroxide2×HCID 105144Allyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)HCID 59424354HCID 59424354, compoundHCID 178418361HCID 178418361, compound

Product 1

HCID 183210463-(Piperidin-4-yl)quinolin-2(1H)-one

Sources & evidence

ORD record
ord-70dbf4def3444ceb9dbbdd209b0cfaa0
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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