Acetaldehyde → 1-Ethyl-4-(4-nitrophenyl)piperidine

HRID 1145753Notes

Reaction equation

HRID 1145753 reaction equation
[C:1]([CH3:2])([O:3][BH-:4]([O:5][C:6](=[O:7])[CH3:8])[O:9][C:10](=[O:11])[CH3:12])=[O:13].[CH:30](=[O:31])[CH3:32].[Cl:38][CH2:39][Cl:40].[N+:15](=[O:16])([O-:17])[c:18]1[cH:19][cH:20][c:21]([CH:24]2[CH2:25][CH2:26][NH:27][CH2:28][CH2:29]2)[cH:22][cH:23]1.[Na+:14].[Na+:37].[O-:33][C:34]([OH:35])=[O:36]>>[CH2:1]([CH3:2])[N:27]1[CH2:26][CH2:25][CH:24]([c:21]2[cH:20][cH:19][c:18]([N+:15](=[O:16])[O-:17])[cH:23][cH:22]2)[CH2:29][CH2:28]1

Participants

7

Reactant 6

HCID 177AcetaldehydeHCID 769Bicarbonate IonHCID 923Sodium ion2×HCID 6344DichloromethaneHCID 2724942TriacetoxyborohydrideHCID 159258174-(4-Nitrophenyl)piperidine

Product 1

HCID 691793941-Ethyl-4-(4-nitrophenyl)piperidine

Sources & evidence

ORD record
ord-04289ab0777a44cb9f82fd33726ad510
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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