Benzonitrile, m-chloro- → 2-Chloro-N-[1-(3-chloro-5'-fluoro-2'-methoxy-biphenyl-4-yl)-ethyl]-4-cyano-benzenesulfonamide

HRID 1145925Notes

Reaction equation

HRID 1145925 reaction equation
[Cl:31][c:32]1[cH:33][c:34](-[c:41]2[c:42]([O:48][CH3:49])[cH:43][cH:44][c:45]([F:47])[cH:46]2)[cH:35][cH:36][c:37]1[CH:38]([CH3:39])[NH2:40].[Cl:55][c:56]1[cH:57][cH:58][cH:59][c:60]([C:62]#[N:63])[cH:61]1.[F:1][c:2]1[cH:3][cH:4][c:5]([O:6][CH3:7])[c:8](-[c:9]2[cH:10][cH:11][c:12]([CH2:13][NH:14][S:15]([c:16]3[cH:17][cH:18][c:19]([O:20][CH3:21])[cH:22][cH:23]3)(=[O:24])=[O:25])[cH:26][c:27]2[O:28][CH3:29])[cH:30]1.[S:50](=[O:51])(=[O:52])([Cl:53])[Cl:54]>>[Cl:31][c:32]1[cH:33][c:34](-[c:41]2[c:42]([O:48][CH3:49])[cH:43][cH:44][c:45]([F:47])[cH:46]2)[cH:35][cH:36][c:37]1[CH:38]([CH3:39])[NH:40][S:50](=[O:51])(=[O:52])[c:57]1[c:56]([Cl:55])[cH:61][c:60]([C:62]#[N:63])[cH:59][cH:58]1

Participants

5

Reactant 4

HCID 13015Benzonitrile, m-chloro-HCID 24648Sulfuryl chlorideHCID 24768914HCID 24768914, compoundHCID 67246860HCID 67246860, compound

Product 1

HCID 672455092-Chloro-N-[1-(3-chloro-5'-fluoro-2'-methoxy-biphenyl-4-yl)-ethyl]-4-cyano-benzenesulfonamide

Sources & evidence

ORD record
ord-ae04ae28415b42ffb808c5ad79fc3abd
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

Loading…