1-(5-Phenylthiophen-2-yl)ethan-1-amine → 1-(5-Phenylthiophen-2-yl)ethan-1-amine

HRID 1145929Notes

Reaction equation

HRID 1145929 reaction equation
[Cl:1][c:2]1[c:3]([NH:19][CH:20]([CH3:21])[c:22]2[cH:23][c:24]([F:31])[c:25]([O:29][CH3:30])[c:26]([F:28])[cH:27]2)[c:4]2[c:5]([cH:17][cH:18]1)[CH2:6][CH2:7][N:8]([C:11](=[O:12])[C:13]([F:14])([F:15])[F:16])[CH2:9][CH2:10]2.[c:32]1(-[c:38]2[cH:39][cH:40][c:41]([CH:43]([CH3:44])[NH2:45])[s:42]2)[cH:33][cH:34][cH:35][cH:36][cH:37]1>>[Cl:1][c:2]1[c:3]([NH:19][CH:20]([CH3:21])[c:22]2[cH:23][c:24]([F:31])[c:25]([O:29][CH3:30])[c:26]([F:28])[cH:27]2)[c:4]2[c:5]([cH:17][cH:18]1)[CH2:6][CH2:7][NH:8][CH2:9][CH2:10]2.[c:32]1(-[c:38]2[cH:39][cH:40][c:41]([CH:43]([CH3:44])[NH2:45])[s:42]2)[cH:33][cH:34][cH:35][cH:36][cH:37]1

Participants

4

Reactant 2

HCID 30320191-(5-Phenylthiophen-2-yl)ethan-1-amineHCID 915831381-[7-Chloro-6-[1-(3,5-difluoro-4-methoxyphenyl)ethylamino]-1,2,4,5-tetrahydro-3-benzazepin-3-yl]-2,2,2-trifluoroethanone

Product 2

HCID 30320191-(5-Phenylthiophen-2-yl)ethan-1-amineHCID 576559787-chloro-N-[1-(3,5-difluoro-4-methoxyphenyl)ethyl]-2,3,4,5-tetrahydro-1H-3-benzazepin-6-amine

Sources & evidence

ORD record
ord-65b5106f3a4f4785bfe83a2eb0d5526a
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

Loading…