{1-[4-(6-Fluoro-4-oxo-2-phenyl-4H-chromen-3-yl)-phenyl]-cyclobutyl}-carbamic acid tert-butyl ester → (1-[4-(8-Methoxy-7-nitro-4-oxo-2-phenyl-4H-chromen-3-yl)-phenyl]-cyclobutyl)-carbamic acid tert-butyl ester
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([NH:7][C:8]1([c:12]2[cH:13][cH:14][c:15](-[c:18]3[c:19](=[O:20])[c:21]4[c:22]([cH:23][cH:24][c:25]([F:26])[cH:27]4)[o:28][c:29]3-[c:30]3[cH:31][cH:32][cH:33][cH:34][cH:35]3)[cH:16][cH:17]2)[CH2:9][CH2:10][CH2:11]1)=[O:36].[I:37][c:38]1[c:39](-[c:54]2[cH:55][cH:56][cH:57][cH:58][cH:59]2)[o:40][c:41]2[c:42]([O:52][CH3:53])[c:43]([N+:49](=[O:50])[O-:51])[cH:44][cH:45][c:46]2[c:47]1=[O:48]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([NH:7][C:8]1([c:12]2[cH:13][cH:14][c:15](-[c:38]3[c:39](-[c:54]4[cH:55][cH:56][cH:57][cH:58][cH:59]4)[o:40][c:41]4[c:42]([O:52][CH3:53])[c:43]([N+:49](=[O:50])[O-:51])[cH:44][cH:45][c:46]4[c:47]3=[O:48])[cH:16][cH:17]2)[CH2:9][CH2:10][CH2:11]1)=[O:36]Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-f3f189ebf7ef4fdb9efc68375af2d0c6
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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