Bicarbonate Ion → Benzyl 4-{4-[3-(2,5-difluorophenoxy)propylamino]phenyl}-3-[4-(3-methoxypropyl)-3,4-dihydro-2H-benzo[1,4]oxazin-6-ylmethoxy]piperidine-1-carboxylate
Reaction equation
[CH3:1][O:2][CH2:3][CH2:4][CH2:5][N:6]1[CH2:7][CH2:8][O:9][c:10]2[c:11]1[cH:12][c:13]([CH2:16][O:17][CH:18]1[CH2:19][N:20]([C:38](=[O:39])[O:40][CH2:41][c:42]3[cH:43][cH:44][cH:45][cH:46][cH:47]3)[CH2:21][CH2:22][CH:23]1[c:24]1[cH:25][cH:26][c:27]([O:30][S:31]([C:32]([F:33])([F:34])[F:35])(=[O:36])=[O:37])[cH:28][cH:29]1)[cH:14][cH:15]2.[F:48][c:49]1[c:50]([O:51][CH2:52][CH2:53][CH2:54][NH2:55])[cH:56][c:57]([F:60])[cH:58][cH:59]1.[Na+:61].[O:66]1[CH2:67][CH2:68][O:69][CH2:70][CH2:71]1.[OH:62][C:63](=[O:64])[O-:65]>>[CH3:1][O:2][CH2:3][CH2:4][CH2:5][N:6]1[CH2:7][CH2:8][O:9][c:10]2[c:11]1[cH:12][c:13]([CH2:16][O:17][CH:18]1[CH2:19][N:20]([C:38](=[O:39])[O:40][CH2:41][c:42]3[cH:43][cH:44][cH:45][cH:46][cH:47]3)[CH2:21][CH2:22][CH:23]1[c:24]1[cH:25][cH:26][c:27]([NH:55][CH2:54][CH2:53][CH2:52][O:51][c:50]3[c:49]([F:48])[cH:59][cH:58][c:57]([F:60])[cH:56]3)[cH:28][cH:29]1)[cH:14][cH:15]2Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-0a6d623e49704dae928b01d46ba11a65
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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